BCLAF1 antibody (AA 250-330)

Catalog No. ABIN7213858

The Rabbit Polyclonal anti-BCLAF1 antibody (ABIN7213858) specifically detects BCLAF1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BCLAF1 antibody (AA 250-330) (ABIN7213858)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCLAF1 Antibody

Binding Specificity: AA 250-330

Purpose: Rabbit Anti-BTF Polyclonal Antibody

Specificity: BTF Polyclonal Antibody detects endogenous levels of BTF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BTF at AA range: 250-330

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BTF

Background: BCLAF1, BTF, KIAA0164, Bcl-2-associated transcription factor 1, BtfBCLAF1encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein (BCL2 associated transcription factor 1) induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for BCLAF1.

Molecular Weight: 106kD

Gene ID: 9774

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus