BCL2L12 antibody (AA 60-140)

Catalog No. ABIN7225300

The Rabbit Polyclonal anti-BCL2L12 antibody is suitable to detect BCL2L12 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for BCL2L12 antibody (AA 60-140) (ABIN7225300)

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCL2L12 Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-BCL2L12 Polyclonal Antibody

Specificity: BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BCL2L12 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCL2L12

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Alternative Name: BCL2L12

Background: BCL2L12, BPR, Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich proteinBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome 3. Alternative splicing results in multiple transcript variants.

Molecular Weight: 34kD

Gene ID: 83596

UniProt: Q9HB09