BCL2L2 antibody (AA 100-180)

Catalog No. ABIN7213788

The Rabbit Polyclonal anti-BCL2L2 antibody (ABIN7213788) specifically detects BCL2L2 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BCL2L2 antibody (AA 100-180) (ABIN7213788)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BCL2L2 Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-Bcl-w Polyclonal Antibody

Specificity: Bcl-w Polyclonal Antibody detects endogenous levels of Bcl-w protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Bcl-w at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: Bcl-w

Background: BCL2L2, BCLW, KIAA0271, Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-WBCL2L2 encodes a member (BCL2 like 2)of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of BCL2L2 in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly (A) binding protein, nuclear 1) gene.

Molecular Weight: 25kD

Gene ID: 599

UniProt: Q92843