BOK antibody (AA 10-90)

Catalog No. ABIN7227512

This Rabbit Polyclonal antibody specifically detects BOK in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BOK antibody (AA 10-90) (ABIN7227512)

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOK antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-BOK Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-BOK Polyclonal Antibody

Specificity: The antibody detects endogenous levels of BOK protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human BOK protein at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BOK

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Alternative Name: BOK

Background: Bcl-2-related ovarian killer protein, hBOK, Bcl-2-like protein 9, Bcl2-L-9BOK encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.

Molecular Weight: 23kD

Gene ID: 666

UniProt: Q9UMX3

Pathways: Positive Regulation of Endopeptidase Activity