B2MG antibody (AA 40-120)
Quick Overview for B2MG antibody (AA 40-120) (ABIN7227440)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-120
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Purpose
- Rabbit Anti-B2MG Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of B2MG protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human B2MG protein at AA range: 40-120
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- B2MG (beta-2-Microglobulin Precursor (B2MG))
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Alternative Name
- B2MG
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Background
- Beta-2-microglobulinB2M encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in B2M has been shown to result in hypercatabolic hypoproteinemia.
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Molecular Weight
- 13kD
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Gene ID
- 567
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UniProt
- P61769
Target
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