BLOC1S1 antibody (AA 50-130)

Catalog No. ABIN7231198

This Rabbit Polyclonal antibody specifically detects BLOC1S1 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for BLOC1S1 antibody (AA 50-130) (ABIN7231198)

Target: BLOC1S1 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLOC1S1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-BLOC1S1 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-RT14 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RT14 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RT14 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BLOC1S1

Target: BLOC1S1 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1))

Alternative Name: RT14

Background: 28S ribosomal protein S14, mitochondrial, MRP-S14, S14mt, Mitochondrial small ribosomal subunit protein uS14 mMitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS14 encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants.

Molecular Weight: 14kD

Gene ID: 63931

UniProt: O60783