BLCAP antibody (AA 10-90)

Catalog No. ABIN7219178

The Rabbit Polyclonal anti-BLCAP antibody is suitable to detect BLCAP in samples from Human, Rat and Mouse. It has been validated for ELISA and IF.

Quick Overview for BLCAP antibody (AA 10-90) (ABIN7219178)

Target: BLCAP (Bladder Cancer Associated Protein (BLCAP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLCAP antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-BLCAP Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-Bc10 Polyclonal Antibody

Specificity: Bc10 Polyclonal Antibody detects endogenous levels of Bc10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Bc10 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BLCAP

Target: BLCAP (Bladder Cancer Associated Protein (BLCAP))

Alternative Name: Bc10

Background: BLCAP, BC10, Bladder cancer-associated protein, Bladder cancer 10 kDa protein, Bc10BLCAP encodes a protein that reduces cell growth by stimulating apoptosis. Alternative splicing and the use of alternative promoters result in multiple transcript variants encoding the same protein. BLCAP is imprinted in brain where different transcript variants are expressed from each parental allele. Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele, while transcript variants initiating downstream of the interspersed NNAT gene (GeneID: 4826) are expressed from the paternal allele. Transcripts at this locus may also undergo A to I editing, resulting in amino acid changes at three positions in the N-terminus of the protein.

Gene ID: 10904

UniProt: P62952