BMP3 antibody (AA 250-330)

Catalog No. ABIN7213820

The Rabbit Polyclonal anti-BMP3 antibody is suitable to detect BMP3 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for BMP3 antibody (AA 250-330) (ABIN7213820)

Target: BMP3 (Bone Morphogenetic Protein 3 (BMP3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BMP3 Antibody

Binding Specificity: AA 250-330

Purpose: Rabbit Anti-BMP-3A Polyclonal Antibody

Specificity: BMP-3A Polyclonal Antibody detects endogenous levels of BMP-3A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BMP-3A at AA range: 250-330

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BMP3

Target: BMP3 (Bone Morphogenetic Protein 3 (BMP3))

Alternative Name: BMP-3A

Background: BMP3, BMP3A, Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, OsteogeninBMP3 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.

Molecular Weight: 55kD

Gene ID: 651

UniProt: P12645