SH2D3 antibody

Catalog No. ABIN7231344

The Rabbit Polyclonal anti-SH2D3 antibody (ABIN7231344) specifically detects SH2D3 in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for SH2D3 antibody (ABIN7231344)

Target: SH2D3 (LOC105225657) (Breast Cancer Anti-Estrogen Resistance Protein 3 Homolog (LOC105225657))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SH2D3 Antibody

Purpose: Rabbit Anti-SH2D3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SH2D3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SH2D3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SH2D3

Target: SH2D3 (LOC105225657) (Breast Cancer Anti-Estrogen Resistance Protein 3 Homolog (LOC105225657))

Alternative Name: SH2D3

Background: SH2 domain-containing protein 3C, Novel SH2-containing protein 3, SH2 domain-containing Eph receptor-binding protein 1, SHEP1SH2D3C (SH2 Domain Containing 3C) encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for SH2D3C.

Molecular Weight: 94kD

Gene ID: 10044

UniProt: Q8N5H7