BCAN antibody

Catalog No. ABIN7230604

The Rabbit Polyclonal anti-BCAN antibody (ABIN7230604) specifically detects BCAN in WB and ELISA. The antibody is reactive with Rat, Human and Mouse samples.

Quick Overview for BCAN antibody (ABIN7230604)

Target: BCAN (Brevican (BCAN))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCAN Antibody

Purpose: Rabbit Anti-PGCB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PGCB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PGCB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCAN

Target: BCAN (Brevican (BCAN))

Alternative Name: PGCB

Background: Brevican core protein, Brain-enriched hyaluronan-binding protein, BEHAB, Chondroitin sulfate proteoglycan 7BCAN encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. Brevican is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants.

Molecular Weight: 100kD

Gene ID: 63827

UniProt: Q96GW7

Pathways: Glycosaminoglycan Metabolic Process