BTBD14A antibody (AA 380-460)

Catalog No. ABIN7229888

This Rabbit Polyclonal antibody specifically detects BTBD14A in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for BTBD14A antibody (AA 380-460) (ABIN7229888)

Target: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD14A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BTBD14A Antibody

Binding Specificity: AA 380-460

Purpose: Rabbit Anti-NAC2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NAC2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NAC2 protein at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BTBD14A

Target: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Alternative Name: NAC2

Background: Sodium/calcium exchanger 2, Na(+)/Ca(2+)-exchange protein 2, Solute carrier family 8 member 2SLC8A2 (Solute Carrier Family 8 Member A2) is a Protein Coding gene. Among its related pathways are Calcium signaling pathway and Collagen chain trimerization. Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion.

Molecular Weight: 101kD

Gene ID: 6543

UniProt: Q9UPR5

Pathways: Positive Regulation of Response to DNA Damage Stimulus