Butyrylcholinesterase antibody

Catalog No. ABIN7227890

This Rabbit Polyclonal antibody specifically detects Butyrylcholinesterase in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Butyrylcholinesterase antibody (ABIN7227890)

Target: Butyrylcholinesterase (BCHE)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Butyrylcholinesterase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Butyrylcholinesterase Antibody

Purpose: Rabbit Anti-CHLE Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CHLE protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CHLE protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Alternative Name: CHLE

Background: Cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, PseudocholinesteraseBCHE encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. Butyrylcholinesterase exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.

Molecular Weight: 66kD

Gene ID: 590

UniProt: P06276

Pathways: Peptide Hormone Metabolism