c-FOS antibody (pSer362)

Catalog No. ABIN7213258

The Rabbit Polyclonal anti-c-FOS antibody is suitable to detect c-FOS in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC, IF and Co-IP.

Quick Overview for c-FOS antibody (pSer362) (ABIN7213258)

Target: c-FOS (c-Fos) (c-Fos)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-FOS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Co-Immunoprecipitation ( Co-IP)

Product Details anti-c-FOS Antibody

Binding Specificity: pSer362

Purpose: Rabbit Anti-c-Fos (phospho Ser362) Polyclonal Antibody

Specificity: Phospho-c-Fos (S362) Polyclonal Antibody detects endogenous levels of c-Fos protein only when phosphorylated at S362.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human c-Fos Phospho-Ser362

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Alternative Name: c-Fos

Background: FOS, G0S7, Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Molecular Weight: 62kD

Gene ID: 2353

UniProt: P01100

Pathways: S100 Proteins