CXL14 antibody

Catalog No. ABIN7228112

This Rabbit Polyclonal antibody specifically detects CXL14 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for CXL14 antibody (ABIN7228112)

Target: CXL14 (C-X-C Motif Chemokine 14 (CXL14))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXL14 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CXL14 Antibody

Purpose: Rabbit Anti-CXL14 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CXL14 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CXL14 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CXL14

Target: CXL14 (C-X-C Motif Chemokine 14 (CXL14))

Alternative Name: CXL14

Background: C-X-C motif chemokine 14, Chemokine BRAK, MIP-2G, Small-inducible cytokine B14CXCL14 belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. CXCL14 (C-X-C Motif Chemokine Ligand 14) is a Protein Coding gene. Diseases associated with CXCL14 include Squamous Cell Carcinoma, Head And Neck and Pelvic Lipomatosis. Among its related pathways are Akt Signaling and PEDF Induced Signaling.

Molecular Weight: 12kD

Gene ID: 9547

UniProt: O95715