CHP antibody (Internal Region)

Catalog No. ABIN7219292

The Rabbit Polyclonal anti-CHP antibody is suitable to detect CHP in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for CHP antibody (Internal Region) (ABIN7219292)

Target: CHP (Calcium Binding Protein P22 (CHP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHP Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CHP Polyclonal Antibody

Specificity: CHP Polyclonal Antibody detects endogenous levels of CHP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CHP

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHP

Target: CHP (Calcium Binding Protein P22 (CHP))

Alternative Name: CHP

Background: CHP1, CHP, Calcineurin B homologous protein 1, Calcineurin B-like protein, Calcium-binding protein CHP, Calcium-binding protein p22, EF-hand calcium-binding domain-containing protein p22CHP1 encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. Calcineurin B homologous protein 1 serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.

Molecular Weight: 24kD

Gene ID: 11261

UniProt: Q99653

Pathways: Proton Transport, Regulation of Carbohydrate Metabolic Process, VEGF Signaling