CaMKIIbeta/gamma/delta antibody (pThr287)

Catalog No. ABIN7201896

The Rabbit Polyclonal anti-CaMKIIbeta/gamma/delta antibody is suitable to detect CaMKIIbeta/gamma/delta in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for CaMKIIbeta/gamma/delta antibody (pThr287) (ABIN7201896)

Target: CaMKIIbeta/gamma/delta

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CaMKIIbeta/gamma/delta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CaMKIIbeta/gamma/delta Antibody

Binding Specificity: pThr287

Purpose: Rabbit Anti-CaMKIIβ/γ/δ (phospho Thr287) Polyclonal Antibody

Specificity: Phospho-CaMKIIβ/γ/δ (T287) Polyclonal Antibody detects endogenous levels of CaMKIIβ/γ/δ protein only when phosphorylated at T287.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CaMKIIbeta/gamma/delta Phospho-Thr287

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200,WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CaMKIIbeta/gamma/delta

Target: CaMKIIbeta/gamma/delta

Background: CAMK2B, CAM2, CAMK2, CAMKB, Calcium/calmodulin-dependent protein kinase type II subunit beta, CaM kinase II subunit beta, CaMK-II subunit beta, CAMK2G, CAMK, CAMK-II, CAMKG, Calcium/calmodulin-dependent protein kinase type II subunit gamma,The product of CAMK2B (calcium/calmodulin dependent protein kinase II beta) belongs to the serine/threonine protein kinase family and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of CAMK2B is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.

Molecular Weight: 50kD,65kD

Gene ID: 816, 818, 817

UniProt: Q13554, Q13555, Q13557