CLIP2 antibody (AA 960-1040)

Catalog No. ABIN7214236

The Rabbit Polyclonal anti-CLIP2 antibody (ABIN7214236) specifically detects CLIP2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CLIP2 antibody (AA 960-1040) (ABIN7214236)

Target: CLIP2 (CAP-GLY Domain Containing Linker Protein 2 (CLIP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLIP2 Antibody

Binding Specificity: AA 960-1040

Purpose: Rabbit Anti-CLIP-115 Polyclonal Antibody

Specificity: CLIP-115 Polyclonal Antibody detects endogenous levels of CLIP-115 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human CLIP-115 at AA range: 960-1040

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CLIP2

Target: CLIP2 (CAP-GLY Domain Containing Linker Protein 2 (CLIP2))

Alternative Name: CLIP-115

Background: CLIP2, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR4, CAP-Gly domain-containing linker protein 2, Cytoplasmic linker protein 115, CLIP-115, Cytoplasmic linker protein 2, Williams-Beuren syndrome chromosomal region 3 protein, Williams-Beuren syndroCAP-Gly domain containing linker protein 2 encoded by CLIP2 belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. CLIP2 is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

Molecular Weight: 120kD

Gene ID: 7461

UniProt: Q9UDT6

Pathways: Microtubule Dynamics