CA4 antibody (Internal Region)

Catalog No. ABIN7217806

The Rabbit Polyclonal anti-CA4 antibody is suitable to detect CA4 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for CA4 antibody (Internal Region) (ABIN7217806)

Target: CA4 (Carbonic Anhydrase IV (CA4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CA4 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CA IV Polyclonal Antibody

Specificity: CA IV Polyclonal Antibody detects endogenous levels of CA IV protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CA IV

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CA4

Target: CA4 (Carbonic Anhydrase IV (CA4))

Alternative Name: CA IV

Background: CA4, Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IVCarbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA4 encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.

Molecular Weight: 35kD

Gene ID: 762

UniProt: P22748