CES2 antibody (Internal Region)

Catalog No. ABIN7225668

The Rabbit Polyclonal anti-CES2 antibody (ABIN7225668) specifically detects CES2 in WB, IHC, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for CES2 antibody (Internal Region) (ABIN7225668)

Target: CES2 (Carboxylesterase 2 (CES2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CES2 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CES2 Polyclonal Antibody

Specificity: CES2 Polyclonal Antibody detects endogenous levels of CES2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CES2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CES2

Target: CES2 (Carboxylesterase 2 (CES2))

Alternative Name: CES2

Background: CES2, ICE, Cocaine esterase, Carboxylesterase 2, CE-2, hCE-2, Methylumbelliferyl-acetate deacetylase 2CES2 (carboxylesterase 2) encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by CES2 is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for CES2.

Molecular Weight: 61kD

Gene ID: 8824

UniProt: O00748