CPA1
Reactivity: Human
IF, FACS
Host: Mouse
Monoclonal
CA2
APC
Application Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
CPA1
(Carboxypeptidase A1 (Pancreatic) (CPA1))
Alternative Name
CPA1
Background
CPA1, CPA, Carboxypeptidase A1CPA1 encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme (carboxypeptidase A1) is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in CPA1 may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.