CPN1 antibody (AA 380-460)

Catalog No. ABIN7214318

The Rabbit Polyclonal anti-CPN1 antibody has been validated for WB and ELISA. It is suitable to detect CPN1 in samples from Human.

Quick Overview for CPN1 antibody (AA 380-460) (ABIN7214318)

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CPN1 Antibody

Binding Specificity: AA 380-460

Purpose: CPN cat Polyclonal Antibody

Specificity: CPN cat Polyclonal Antibody detects endogenous levels of CPN cat protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human CPN cat at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CPN1

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Alternative Name: CPN

Background: Rabbit Anti-CPN cat Polyclonal Antibody,CPN1, ACBP, Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, S,Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits, CPN1 encodes the catalytic subunit. Mutations in CPN1 can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.,Carboxypeptidase N catalytic chain

Molecular Weight: observerd band 52kDa

Gene ID: 1369

UniProt: P15169

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process