CROT antibody (AA 190-270)

Catalog No. ABIN7223304

The Rabbit Polyclonal anti-CROT antibody is suitable to detect CROT in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for CROT antibody (AA 190-270) (ABIN7223304)

Target: CROT (Carnitine O-Octanoyltransferase (CROT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CROT antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CROT Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-CROT Polyclonal Antibody

Specificity: CROT Polyclonal Antibody detects endogenous levels of CROT protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CROT at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CROT

Target: CROT (Carnitine O-Octanoyltransferase (CROT))

Alternative Name: CROT

Background: CROT, COT, Peroxisomal carnitine O-octanoyltransferase, COTCROT (carnitine O-octanoyltransferase) encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.

Molecular Weight: 72kD

Gene ID: 54677

UniProt: Q9UKG9

Pathways: Monocarboxylic Acid Catabolic Process