CSNK2A1/CK II alpha antibody (pTyr255)

Catalog No. ABIN7219764

The Rabbit Polyclonal anti-CSNK2A1/CK II alpha antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect CSNK2A1/CK II alpha in samples from Human, Mouse and Rat.

Quick Overview for CSNK2A1/CK II alpha antibody (pTyr255) (ABIN7219764)

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK2A1/CK II alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CSNK2A1/CK II alpha Antibody

Binding Specificity: pTyr255

Purpose: Casein Kinase IIα (phospho Tyr255) Polyclonal Antibody

Specificity: Phospho-Casein Kinase IIα (Y255) Polyclonal Antibody detects endogenous levels of Casein Kinase IIα protein only when phosphorylated at Y255.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Casein Kinase IIalpha Phospho-Tyr255

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Alternative Name: Casein Kinase IIalpha

Background: Rabbit Anti-Casein Kinase IIα (phospho Tyr255) Polyclonal Antibody,CSNK2A1, CK2A1, Casein kinase II subunit alpha, CK II alpha,Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.,Casein kinase II subunit alpha

Molecular Weight: observerd band 45kDa

Gene ID: 1457

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interactome