CARD10 antibody (AA 450-530)

Catalog No. ABIN7213936

The Rabbit Polyclonal anti-CARD10 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect CARD10 in samples from Human and Mouse.

Quick Overview for CARD10 antibody (AA 450-530) (ABIN7213936)

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CARD10 Antibody

Binding Specificity: AA 450-530

Purpose: CARD 10 Polyclonal Antibody

Specificity: CARD 10 Polyclonal Antibody detects endogenous levels of CARD 10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CARD 10 at AA range: 450-530

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CARD10

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Alternative Name: CARD 10

Background: Rabbit Anti-CARD 10 Polyclonal Antibody,CARD10, CARMA3, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3, Carma 3,The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).,Caspase recruitment domain-containing protein 10

Molecular Weight: observerd band 120kDa

Gene ID: 29775

UniProt: Q9BWT7

Pathways: S100 Proteins