CARD10 antibody (AA 863-1032)

Catalog No. ABIN6137937

Product Details anti-CARD10 Antibody

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Binding Specificity: AA 863-1032

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: LLDLPSSRLD FQVCPAESLS GEELCPSSAP GAPKAQPATP GLGSRIRAIQ ESVGKKHCLL ELGARGVREL VQNEIYPIVI HVEVTEKNVR EVRGLLGRPG WRDSELLRQC RGSEQVLWGL PCSWVQVPAH EWGHAEELAK VVRGRILQEQ ARLVWVECGS SRGCPSSSEA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 863-1032 of human CARD10 (NP_055365.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CARD10

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Alternative Name: CARD10 (CARD10 Products)

Synonyms: CARD10 antibody, BIMP1 antibody, CARMA3 antibody, AI449026 antibody, Bimp1 antibody, Carma3 antibody, caspase recruitment domain family, member 10 antibody, caspase recruitment domain family member 10 antibody, Card10 antibody, CARD10 antibody

Background: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],CARD10,BIMP1,CARMA3,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD10

Molecular Weight: 82 kDa/115 kDa

Gene ID: 29775

UniProt: Q9BWT7

Pathways: S100 Proteins