CTNND2 antibody

Catalog No. ABIN7228088

This anti-CTNND2 antibody is a Rabbit Polyclonal antibody detecting CTNND2 in ELISA and WB. Suitable for Human and Mouse.

Quick Overview for CTNND2 antibody (ABIN7228088)

Target: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNND2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CTNND2 Antibody

Purpose: CTND2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CTND2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CTND2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CTNND2

Target: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Alternative Name: CTND2

Background: Rabbit Anti-CTND2 Polyclonal Antibody,Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin,CTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.,CTND2

Molecular Weight: observerd band 134kDa

Gene ID: 1501

UniProt: Q9UQB3