CTNND2 antibody (AA 4-308)

Catalog No. ABIN7146992

Product Details anti-CTNND2 Antibody

Target: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Binding Specificity: AA 4-308

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNND2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Catenin delta-2 protein (4-308AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CTNND2

Target: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Alternative Name: CTNND2 (CTNND2 Products)

Synonyms: CTNND2 antibody, Catnd2 antibody, Nprap antibody, neurojugin antibody, GT24 antibody, NPRAP antibody, ctnnd2 antibody, si:dkey-40c17.4 antibody, catenin delta 2 antibody, delta-catenin antibody, catenin delta-2 antibody, catenin (cadherin associated protein), delta 2 antibody, catenin (cadherin-associated protein), delta 2b antibody, CTNND2 antibody, BACOIKO001_27 antibody, LOC100070792 antibody, Ctnnd2 antibody, ctnnd2b antibody

Background:

Background: Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:25807484). Involved in the regulation of Wnt signaling (PubMed:25807484). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.

Aliases: ARM-repeat protein antibody, Catenin (cadherin associated protein) delta 2 antibody, catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody, Catenin delta 2 antibody, Catenin delta-2 antibody, CTND2_HUMAN antibody, CTNND 2 antibody, Ctnnd2 antibody, Delta catenin antibody, Delta-catenin antibody, GT 24 antibody, GT24 antibody, Neural plakophilin related arm repeat protein antibody, Neural plakophilin related armadillo repeat protein antibody, Neural plakophilin-related ARM-repeat protein antibody, Neural plakophilin-related, Neurojungin antibody, Neurojungin antibody, NPRAP antibody, T cell delta catenin antibody

UniProt: Q9UQB3