Cathepsin L2 antibody (Cleaved-Leu114)

Catalog No. ABIN7212464

The Rabbit Polyclonal anti-Cathepsin L2 antibody (ABIN7212464) specifically detects Cathepsin L2 in WB and ELISA. The antibody is reactive with Human and Monkey samples.

Quick Overview for Cathepsin L2 antibody (Cleaved-Leu114) (ABIN7212464)

Target: Cathepsin L2 (CTSL2)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cathepsin L2 Antibody

Binding Specificity: AA 70-150, Cleaved-Leu114

Purpose: Rabbit Anti-Cleaved-Cathepsin L2 (L114) Polyclonal Antibody

Specificity: Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cathepsin L2 at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cathepsin L2

Target: Cathepsin L2 (CTSL2)

Alternative Name: Cathepsin L2

Background: CTSL2, CATL2, CTSU, CTSV, Cathepsin L2, Cathepsin U, Cathepsin VCathepsin V encoded by CTSV, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. CTSV is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for CTSV in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 37kD

Gene ID: 1515

UniProt: O60911

Pathways: Toll-Like Receptors Cascades