Cathepsin Z antibody (Cleaved-Leu62)

Catalog No. ABIN7212466

The Rabbit Polyclonal anti-Cathepsin Z antibody is suitable to detect Cathepsin Z in samples from Human and Monkey. It has been validated for WB and ELISA.

Quick Overview for Cathepsin Z antibody (Cleaved-Leu62) (ABIN7212466)

Target: Cathepsin Z (CTSZ)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin Z antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cathepsin Z Antibody

Binding Specificity: AA 20-100, Cleaved-Leu62

Purpose: Rabbit Anti-Cleaved-Cathepsin Z (L62) Polyclonal Antibody

Specificity: Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cathepsin Z at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cathepsin Z

Target: Cathepsin Z (CTSZ)

Alternative Name: Cathepsin Z

Background: CTSZ, Cathepsin Z, Cathepsin P, Cathepsin XThe protein encoded by CTSZ is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. Cathepsin Z has also been known as cathepsin X and cathepsin P. CTSZ is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.

Molecular Weight: 27kD

Gene ID: 1522

UniProt: Q9UBR2

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones