CD1b antibody (AA 60-100)

Catalog No. ABIN7227704

This Rabbit Polyclonal antibody specifically detects CD1b in ELISA, IF and IHC. It exhibits reactivity toward Human.

Quick Overview for CD1b antibody (AA 60-100) (ABIN7227704)

Target: CD1b (CD1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1b antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-CD1b Antibody

Binding Specificity: AA 60-100

Purpose: Rabbit Anti-CD1B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD1B

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD1B protein at AA range: 60-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD1b

Target: CD1b (CD1B)

Alternative Name: CD1B

Background: T-cell surface glycoprotein CD1b, CD antigen CD1bCD1B encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by CD1B localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Gene ID: 910

UniProt: P29016