CD1e antibody (AA 190-270)

Catalog No. ABIN7214052

The Rabbit Polyclonal anti-CD1e antibody (ABIN7214052) specifically detects CD1e in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CD1e antibody (AA 190-270) (ABIN7214052)

Target: CD1e

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1e antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD1e Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-CD1e Polyclonal Antibody

Specificity: CD1e Polyclonal Antibody detects endogenous levels of CD1e protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD1e at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD1e

Target: CD1e

Alternative Name: CD1e

Background: CD1E, T-cell surface glycoprotein CD1e, membrane-associated, hCD1e, R2G1, CD antigen CD1eCD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein (CD1e molecule) encoded by CD1E localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found, however, their biological validity has not been determined.

Molecular Weight: 36kD

Gene ID: 913

UniProt: P15812