CD207 antibody (Internal Region)

Catalog No. ABIN7218086

This Rabbit Polyclonal antibody specifically detects CD207 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CD207 antibody (Internal Region) (ABIN7218086)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD207 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD207 Antibody

Binding Specificity: Internal Region

Purpose: CD207 Polyclonal Antibody

Specificity: CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CD207

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: CD207

Background: Rabbit Anti-CD207 Polyclonal Antibody,CD207, CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207,C-type lectin domain family 4 member K encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.,C-type lectin domain family 4 member K

Molecular Weight: observerd band 38kDa

Gene ID: 50489

UniProt: Q9UJ71