CD300a antibody (AA 141-190)

Catalog No. ABIN7227736

The Rabbit Polyclonal anti-CD300a antibody is suitable to detect CD300a in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for CD300a antibody (AA 141-190) (ABIN7227736)

Target: CD300a (CD300A)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD300a antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CD300a Antibody

Binding Specificity: AA 141-190

Purpose: Rabbit Anti-CD300a Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD300a

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD300a protein at AA range: 141-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD300a

Target: CD300a (CD300A)

Alternative Name: CD300a

Background: CMRF35-like molecule 8, CLM-8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, IgSF12, Inhibitory receptor protein 60, IRp60, NK inhibitory receptor, CD antigen CD300aCD300A encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. CD300A is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. CD300A (CD300a Molecule) is a Protein Coding gene. Diseases associated with CD300A include Kabuki Syndrome 1. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System.

Gene ID: 11314

UniProt: Q9UGN4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process