CD320 antibody (AA 100-180)

Catalog No. ABIN7227748

The Rabbit Polyclonal anti-CD320 antibody is suitable to detect CD320 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for CD320 antibody (AA 100-180) (ABIN7227748)

Target: CD320 (CD320 Molecule (CD320))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD320 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD320 Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-CD320 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD320 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD320 protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD320

Target: CD320 (CD320 Molecule (CD320))

Alternative Name: CD320

Background: CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, FDC-SM-8D6, Transcobalamin receptor, TCblR, CD320CD320 (CD320 Molecule) is a Protein Coding gene. Diseases associated with CD320 include Methylmalonic Aciduria, Transient, Due To Transcobalamin Receptor Defect and Methylmalonic Acidemia Due To Transcobalamin Receptor Defect. Among its related pathways are Metabolism and HIV Life Cycle. CD320 encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and is involved in B-cell proliferation and immunoglobulin secretion. Mutations in CD320 are associated with methylmalonic aciduria. Alternatively spliced transcript variants encoding different isoforms have been found for CD320.

Molecular Weight: 31kD

Gene ID: 51293

UniProt: Q9NPF0