CDC42EP2 antibody (AA 10-90)

Catalog No. ABIN7218982

The Rabbit Polyclonal anti-CDC42EP2 antibody is suitable to detect CDC42EP2 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for CDC42EP2 antibody (AA 10-90) (ABIN7218982)

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDC42EP2 Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-Cdc42EP2 Polyclonal Antibody

Specificity: Cdc42EP2 Polyclonal Antibody detects endogenous levels of Cdc42EP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Cdc42EP2 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDC42EP2

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Alternative Name: Cdc42EP2

Background: CDC42EP2, BORG1, CEP2, Cdc42 effector protein 2, Binder of Rho GTPases 1CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control.

Molecular Weight: 28kD

Gene ID: 10435

UniProt: O14613

Pathways: Regulation of Actin Filament Polymerization