CDC42EP5 antibody (AA 1-80)

Catalog No. ABIN7214112

The Rabbit Polyclonal anti-CDC42EP5 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect CDC42EP5 in samples from Human and Mouse.

Quick Overview for CDC42EP5 antibody (AA 1-80) (ABIN7214112)

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CDC42EP5 Antibody

Binding Specificity: AA 1-80

Purpose: Cdc42EP5 Polyclonal Antibody

Specificity: Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Cdc42EP5 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CDC42EP5

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Alternative Name: Cdc42EP5

Background: Rabbit Anti-Cdc42EP5 Polyclonal Antibody,CDC42EP5, BORG3, CEP5, Cdc42 effector protein 5, Binder of Rho GTPases 3,Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts.,Cdc42 effector protein 5

Molecular Weight: observerd band 22kDa

Gene ID: 148170

UniProt: Q6NZY7

Pathways: Regulation of Actin Filament Polymerization