CDC42EP5 antibody (Middle Region)

Catalog No. ABIN2785099

Product Details anti-CDC42EP5 Antibody

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HVGRGGDAFG DTSFLSRHGG GPPPEPRAPP AGAPRSPPPP AVPQSAAPSP

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CDC42EP5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC42EP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 148 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC42EP5

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Alternative Name: CDC42EP5 (CDC42EP5 Products)

Synonyms: Borg3 antibody, CEP5 antibody, 1700027J19Rik antibody, 2010007O02Rik antibody, C85526 antibody, CDC42 effector protein 5 antibody, CDC42 effector protein (Rho GTPase binding) 5 antibody, CDC42EP5 antibody, Cdc42ep5 antibody

Background: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.
Alias Symbols: Borg3, CEP5, MGC21945, MGC71153
Protein Interaction Partner: SEPT7, CDC42, Sept6, Sept2,
Protein Size: 148

Molecular Weight: 15 kDa

Gene ID: 148170

NCBI Accession: NM_145057, NP_659494

UniProt: Q6NZY7

Pathways: Regulation of Actin Filament Polymerization