Arhgef9 antibody (AA 370-450)

Catalog No. ABIN7220678

The Rabbit Polyclonal anti-Arhgef9 antibody (ABIN7220678) specifically detects Arhgef9 in ELISA, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Arhgef9 antibody (AA 370-450) (ABIN7220678)

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arhgef9 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Arhgef9 Antibody

Binding Specificity: AA 370-450

Purpose: Rabbit Anti-ARHGEF9 Polyclonal Antibody

Specificity: ARHGEF9 Polyclonal Antibody detects endogenous levels of ARHGEF9 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human ARHGEF9 at AA range: 370-450

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Arhgef9

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Alternative Name: ARHGEF9

Background: ARHGEF9, ARHDH9, KIAA0424, Rho guanine nucleotide exchange factor 9, Collybistin, PEM-2 homolog, Rac/Cdc42 guanine nucleotide exchange factor 9The Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Gene ID: 23229

UniProt: O43307

Pathways: Neurotrophin Signaling Pathway