CENPI antibody (AA 10-90)

Catalog No. ABIN7227830

The Rabbit Polyclonal anti-CENPI antibody (ABIN7227830) specifically detects CENPI in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CENPI antibody (AA 10-90) (ABIN7227830)

Target: CENPI (Centromere Protein I (CENPI))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPI antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CENPI Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-CENPI Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CENPI protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CENPI protein at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CENPI

Target: CENPI (Centromere Protein I (CENPI))

Alternative Name: CENPI

Background: Centromere protein I, CENP-I, FSH primary response protein 1, Follicle-stimulating hormone primary response protein, Interphase centromere complex protein 19, Leucine-rich primary response protein 1CENPI (Centromere Protein I) encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of CENPI is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of CENPI is found on chromosome 13.

Molecular Weight: 83kD

Gene ID: 2491

UniProt: Q92674