CEP170 antibody (AA 670-750)

Catalog No. ABIN7214144

The Rabbit Polyclonal anti-CEP170 antibody (ABIN7214144) specifically detects CEP170 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for CEP170 antibody (AA 670-750) (ABIN7214144)

Target: CEP170 (Centrosomal Protein 170kDa (CEP170))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP170 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CEP170 Antibody

Binding Specificity: AA 670-750

Purpose: Rabbit Anti-CEP170 Polyclonal Antibody

Specificity: CEP170 Polyclonal Antibody detects endogenous levels of CEP170 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CEP170 at AA range: 670-750

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CEP170

Target: CEP170 (Centrosomal Protein 170kDa (CEP170))

Alternative Name: CEP170

Background: CEP170, FAM68A, KAB, KIAA0470, Centrosomal protein of 170 kDa, Cep170, KARP-1-binding protein, KARP1-binding proteinThe product of CEP170 is a component of the centrosome, a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of CEP170 have been found, but the full-length nature of some of these variants has not been determined.

Molecular Weight: 160kD

Gene ID: 9859

UniProt: Q5SW79