CEP290 antibody (AA 740-820)

Catalog No. ABIN7214146

This Rabbit Polyclonal antibody specifically detects CEP290 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for CEP290 antibody (AA 740-820) (ABIN7214146)

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP290 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CEP290 Antibody

Binding Specificity: AA 740-820

Purpose: CEP290 Polyclonal Antibody

Specificity: CEP290 Polyclonal Antibody detects endogenous levels of CEP290 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CEP290 at AA range: 740-820

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Alternative Name: CEP290

Background: Rabbit Anti-CEP290 Polyclonal Antibody,CEP290, BBS14, KIAA0373, NPHP6, Centrosomal protein of 290 kDa, Cep290, Bardet-Biedl syndrome 14 protein, Cancer/testis antigen 87, CT87, Nephrocystin-6, Tumor antigen se2-2,CEP290 encodes a protein (centrosomal protein 290) with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in CEP290 have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.,Centrosomal protein of 290 kDa

Molecular Weight: observerd band 290kDa

Gene ID: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase