CERKL antibody (AA 310-390)

Catalog No. ABIN7214160

This Rabbit Polyclonal antibody specifically detects CERKL in ELISA, WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CERKL antibody (AA 310-390) (ABIN7214160)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERKL antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CERKL Antibody

Binding Specificity: AA 310-390

Purpose: CERKL Polyclonal Antibody

Specificity: CERKL Polyclonal Antibody detects endogenous levels of CERKL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CERKL at AA range: 310-390

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Alternative Name: CERKL

Background: Rabbit Anti-CERKL Polyclonal Antibody,CERKL, Ceramide kinase-like protein,CERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.,Ceramide kinase-like protein

Molecular Weight: observerd band 63kDa

Gene ID: 375298

UniProt: Q49MI3