CER1 antibody (Internal Region)

Catalog No. ABIN7218344

The Rabbit Polyclonal anti-CER1 antibody (ABIN7218344) specifically detects CER1 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for CER1 antibody (Internal Region) (ABIN7218344)

Target: CER1 (Cerberus 1 Homolog (Xenopus Laevis) (CER1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CER1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CER1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Cerberus Polyclonal Antibody

Specificity: Cerberus Polyclonal Antibody detects endogenous levels of Cerberus protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cerberus

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CER1

Target: CER1 (Cerberus 1 Homolog (Xenopus Laevis) (CER1))

Alternative Name: Cerberus

Background: CER1, DAND4, Cerberus, Cerberus-related protein, DAN domain family member 4CER1 encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.

Molecular Weight: 30kD

Gene ID: 9350

UniProt: O95813

Pathways: Maintenance of Protein Location