CLN3 antibody (AA 221-270)

Catalog No. ABIN7227948

The Rabbit Polyclonal anti-CLN3 antibody is suitable to detect CLN3 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for CLN3 antibody (AA 221-270) (ABIN7227948)

Target: CLN3 (Ceroid-Lipofuscinosis, Neuronal 3 (CLN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLN3 Antibody

Binding Specificity: AA 221-270

Purpose: Rabbit Anti-CLN3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CLN3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CLN3 protein at AA range: 221-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CLN3

Target: CLN3 (Ceroid-Lipofuscinosis, Neuronal 3 (CLN3))

Alternative Name: CLN3

Background: Battenin, Batten disease protein, Protein CLN3CLN3 encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for CLN3.

Molecular Weight: 48kD

Gene ID: 1201

UniProt: Q13286