CCT5 antibody (AA 210-290)

Catalog No. ABIN7220588

This Rabbit Polyclonal antibody specifically detects CCT5 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CCT5 antibody (AA 210-290) (ABIN7220588)

Target: CCT5 (Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCT5 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-TCP-1 ε Polyclonal Antibody

Specificity: TCP-1 ε Polyclonal Antibody detects endogenous levels of TCP-1 ε protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TCP-1 epsilon at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCT5

Target: CCT5 (Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5))

Alternative Name: TCP-1 epsilon

Background: CCT5, CCTE, KIAA0098, T-complex protein 1 subunit epsilon, TCP-1-epsilon, CCT-epsilonThe chaperonin containing TCP1 subunit 5 encoded by CCT5 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.

Molecular Weight: 67kD

Gene ID: 22948

UniProt: P48643