XCR1 antibody (AA 160-240)

Catalog No. ABIN7232180

The Rabbit Polyclonal anti-XCR1 antibody is suitable to detect XCR1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for XCR1 antibody (AA 160-240) (ABIN7232180)

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-XCR1 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-XCR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of XCR1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human XCR1 protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for XCR1

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Alternative Name: XCR1

Background: Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1The protein encoded by XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for XCR1.

Molecular Weight: 36kD

Gene ID: 2829

UniProt: P46094