CCL27 antibody (Internal Region)

Catalog No. ABIN7226702

The Rabbit Polyclonal anti-CCL27 antibody is suitable to detect CCL27 in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for CCL27 antibody (Internal Region) (ABIN7226702)

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL27 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CCL27 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CTACK Polyclonal Antibody

Specificity: CTACK Polyclonal Antibody detects endogenous levels of CTACK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CTACK

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCL27

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Alternative Name: CTACK

Background: CCL27, ILC, SCYA27, C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27CCL27 (C-C motif chemokine ligand 27) is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Molecular Weight: 12kD

Gene ID: 10850

UniProt: Q9Y4X3