CCR9 antibody (AA 140-220)

Catalog No. ABIN7227678

The Rabbit Polyclonal anti-CCR9 antibody (ABIN7227678) specifically detects CCR9 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CCR9 antibody (AA 140-220) (ABIN7227678)

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCR9 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-CCR9 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCR9 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCR9 protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CCR9

Background: C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CD_antigen: CDw199The protein encoded by CCR9 is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that CCR9 is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. CCR9 is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for CCR9.

Molecular Weight: 42kD

Gene ID: 10803

UniProt: P51686