CLCN1 antibody

Catalog No. ABIN7227934

The Rabbit Polyclonal anti-CLCN1 antibody is suitable to detect CLCN1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CLCN1 antibody (ABIN7227934)

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLCN1 Antibody

Purpose: Rabbit Anti-CLCN1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CLCN1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CLCN1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CLCN1

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Alternative Name: CLCN1

Background: Chloride channel protein 1, ClC-1, Chloride channel protein, skeletal muscleCLCN1 (Chloride Voltage-Gated Channel 1) is a Protein Coding gene. Diseases associated with CLCN1 include Myotonia Congenita, Recessive and Myotonia Congenita, Dominant The protein encoded by CLCN1 regulates the electric excitability of the skeletal muscle membrane. Mutations in CLCN1 cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.

Molecular Weight: 108kD

Gene ID: 1180

UniProt: P35523