CLCN2 antibody

Catalog No. ABIN7227936

The Rabbit Polyclonal anti-CLCN2 antibody (ABIN7227936) specifically detects CLCN2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CLCN2 antibody (ABIN7227936)

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLCN2 Antibody

Purpose: Rabbit Anti-CLCN2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CLCN2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CLCN2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CLCN2

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Alternative Name: CLCN2

Background: Chloride channel protein 2, ClC-2CLCN2 (Chloride Voltage-Gated Channel 2) is a Protein Coding gene. Diseases associated with CLCN2 include Leukoencephalopathy With Ataxia and Epilepsy, Idiopathic Generalized 11. Among its related pathways are Hepatic ABC Transporters and Activation of cAMP-Dependent PKA. CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in CLCN2 may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for CLCN2.

Molecular Weight: 98kD

Gene ID: 1181

UniProt: P51788